Journal article

The cyclobutene diester approach to alkyl citrate natural products

Nikolai P Rossouw, Mark A Rizzacasa

AUSTRALIAN JOURNAL OF CHEMISTRY | CSIRO PUBLISHING | Published : 2024

Abstract

This review outlines the synthesis of alkyl citrate natural products using cyclobutene diester precursors. The approach is efficient and stereoselective and provides the correct oxidation state of the citrate core of these compounds. The synthesis of a number of alkyl citrates along with some higher oxidised members of this family is detailed.

University of Melbourne Researchers